Thank you for helping me ID the wild poinsettia.
Now I have another mystery plant- it is also
growing in a shady spot of our backyard in Charleston, SC.
Virginia, I can see this would be a tricky one, because some of the leaves have turned white and have dead tissue. However, the whorls of 4 leaves as well as the immature pendulous fruit tell me that this is a bedstraw, or Galium. I am not 100 % sure of the species, but given your location and the rather tough appearance of this species, I would say it is Galium hispidulum.
Sincerely, Steve Hill, SCNPS, Botanist