Viny plant with a very strange flowering structure. Growing in an open area at the edge of a large swamp near North Augusta, SC
I’m not sure what the vine is from that picture, but you are dealing with either an insect gall or a fungus on this plant. It is not a flowering structure. If you want the host identified I will need a picture showing more of the plant. I could guess it is poison ivy – but that is only a guess.
–Steve Hill (Ph.D.) SCNPS